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Personal Information





Date of birth

17 Ottobre, 1980

Contact Details


Departmemnt of Industrial Engineering Rome Tor Vergata University Via del Politecnico 1, 00133 Rome, Italy

Office Location

Building of Industrial Engineering, I floor, Room n. 1080


39 328 7468581


Native Language



Reading skills: good
Writing skills: good
Verbal skills: good


Current Position

Associate professor in Fluid Dynamics (SSD ING-IND/06, SC 09/A1)
Rome Tor Vergata University – Department of Industrial Engineering.


Master Degree in Aerospace Engineering at the University of Rome La Sapienza

PhD in Theoretical and Applied Mechanics at the University of Rome La Sapienza


Gas Dynamics – 6 CFU
Turbulence and complex flows – 6 CFU
Nanoscale Energy Technology, Nano-Sensors and Microfluidics – 3 CFU

Research Activities

• Mass and ion transport in biological and solid-state nanochannels
• Nanopore sensing of biomolecules, theoretical and computational approaches
• Computational models of microoswimmers
• Atomistic and Coarse grained models of electroosmotic flows
• Wetting, Cavitation and Boiling over nanostructured surfaces

Web Pages

Google Scholar

Publications (last 5 years)

Publications (last 5 years)
  1. Cecconi, F., & Chinappi, M. (2020). Native-state fingerprint on the ubiquitin translocation across a nanopore. Physical Review E, 101(3), 032401.
  2. Giamblanco, N., Janot, J. M., Gubbiotti, A., Chinappi, M., & Balme, S. (2020). Characterization of Food Amyloid Protein Digestion by Conical Nanopore. Small Methods, 1900703.
  3. Asandei, A., Di Muccio, G., Schiopu, I., Mereuta, L., Dragomir, I. S., Chinappi, M., & Luchian, T. (2020). Nanopore‐Based Protein Sequencing Using Biopores: Current Achievements and Open Challenges. Small Methods, 1900595.
  4. Silvani, G., Scognamiglio, C., Caprini, D., Marino, L., Chinappi, M., Sinibaldi, G., Peruzzi, G., Kiani, M.F. and Casciola, C.M., (2019). Reversible Cavitation‐Induced Junctional Opening in an Artificial Endothelial Layer. Small, 15(51), p.1905375.
  5. A. Gubbiotti, M. Chinappi and C. Casciola, (2019) Confinement effects on the dynamics of a rigid particle in a nanochannel, Physical Review E, 100(5), 053307
  6. G. Di Muccio, A. E. Rossini, D. Di Marino, G. Zollo, and M. Chinappi, (2019) Insights into protein sequencing with an α-Hemolysin nanopore by atomistic simulations. Scientific reports, 9(1), 6440.
  7. E. L. Bonome, F. Cecconi and M. Chinappi, (2019) Translocation intermediates of Ubiquitin through an α-Hemolysin nanopore: implications for detection of post-translational modifications. Nanoscale. 11, 9920-9930
  8. M. Chinappi and P Malgaretti, (2018) Charge polarization, local electroneutrality breakdown and eddy formation due to electroosmosis in varying-section channels. Soft matter, 14(45), 9083-9087.
  9. Giamblanco, N., Coglitore, D., Gubbiotti, A., Ma, T., Balanzat, E., Janot, J. M., Chinappi, M. & Balme, S. (2018). Amyloid growth, inhibition and real-time enzymatic degradation revealed with single conical nanopore. Analytical chemistry, 90(21), 12900-12908..
  10. Chinappi, M., & Cecconi, F. (2018). Protein sequencing via nanopore based devices: a nanofluidics perspective. Journal of Physics: Condensed Matter, 30(20), 204002.
  11. Asandei, A., Dragomir, I., Di Muccio, G., Chinappi, M., Park, Y., & Luchian, T. (2018). Single-Molecule Dynamics and Discrimination between Hydrophilic and Hydrophobic Amino Acids in Peptides, through Controllable, Stepwise Translocation across Nanopores. Polymers, 10(8), 885.
  12. Besharat, Z. M., Abballe, L., Cicconardi, F., Bhutkar, A., Grassi, L., Le Pera, L., Moretti, M., Chinappi, M., & … Ferretti, E. (2018). Foxm1 controls a pro-stemness microRNA network in neural stem cells. Scientific reports, 8(1), 3523.
  13. Rossini, A. E., Gala, F., Chinappi, M., & Zollo, G. (2018). Peptide bonds detection via graphene nanogaps: a proof of principles study. Nanoscale 10, no. 13 (2018): 5928-5937.
  14. Pimponi, D., Chinappi, M., & Gualtieri, P. (2018). Flagellated microswimmers: Hydrodynamics in thin liquid films. The European Physical Journal E, 41(2), 28.
  15. Sinibaldi, G., Iebba, V., & Chinappi, M. (2018). Swimming and rafting of E. coli microcolonies at air–liquid interfaces. MicrobiologyOpen, Vol. 1873, No. 1, p. 020010.
  16. Guccione, G., Pimponi, D., Gualtieri, P., & Chinappi, M. (2017). Diffusivity of E. Coli-like microswimmers in confined geometries: The role of the tumbling rate. Physical Review E, 96(4), 042603
  17. Bonome, E. L., Cecconi, F., & Chinappi, M. (2017). Electroosmotic flow through analpha-hemolysin nanopore. Microfluidics and Nanofluidics, 21(5), 99
  18. Asandei, A., Rossini, A. E., Chinappi, M., Park, Y., & Luchian, T. (2017). Protein Nanopore-Based Discrimination between Selected Neutral Amino Acids from Polypeptides. Langmuir, 33(50), 14451-14459.
  19. Watanabe, H., Gubbiotti, A., Chinappi, M., Takai, N., Tanaka, K., Tsumoto, K., & Kawano, R. (2017). Analysis of Pore Formation and Protein Translocation Using Large Biological Nanopores. Analytical Chemistry. 89, no. 21 (2017): 11269-11277
  20. Asandei, A., Schiopu, I., Chinappi, M., Seo, C. H., Park, Y., & Luchian, T. (2016). An Electroosmotic Trap Against the Electrophoretic Force Near a Protein Nanopore Reveals Peptide Dynamics During Capture and Translocation. ACS Applied Materials & Interfaces, 8 (20), pp 13166–13179
  21. D. Pimponi, M. Chinappi, P. Gualtieri, C. M. Casciola, (2016) Hydrodynamics of flagellated microswimmers near free-slip interfaces, J. Fluid Mechanics, Volume 789, pp 514-533
  22. M. Chinappi, T. Luchian, F. Cecconi, (2015) Nanopore tweezers: Voltage-controlled trapping and releasing of analytes, Phys. Rev. E, 92, no. 3 (2015): 032714.
  23. D. Di Marino, E.L. Bonome, A. Tramontano, M. Chinappi, (2015) All-Atom Molecular Dynamics Simulation of Protein Translocation through an α-Hemolysin Nanopore, J. Phys. Chem. Lett. 6(15), 2963-2968.
  24. A. Asandei, M. Chinappi, H-k Kang, C. H. Seo, L. Mereuta, Y. Park, and T. Luchian, (2015) Placement of oppositely charged aminoacids at a polypeptide termini determines the voltage-controlled braking of polymer transport through nanometer-scale pores, Scientific Reports, 5 (2015): 10419.
  25. Asandei, A., Chinappi, M., Kang, H. K., Seo, C. H., Mereuta, L., Park, Y., & Luchian, T. (2015). Acidity-mediated, electrostatic tuning of asymmetrically charged peptides interactions with protein nanopores. ACS applied materials & interfaces, 7(30), 16706-16714.
  26. Ansalone, P., Chinappi, M., Rondoni, L., & Cecconi, F. (2015). Driven diffusion against electrostatic or effective energy barrier across α-hemolysin. The Journal of chemical physics, 143(15), 154109.
  27. Plata, C. A., Cecconi, F., Chinappi, M., & Prados, A. (2015). Understanding the dependence on the pulling speed of the unfolding pathway of proteins. Journal of Statistical Mechanics: Theory and Experiment, 2015(8), P08003.
  28. Bonome, E. L., Lepore, R., Raimondo, D., Cecconi, F., Tramontano, A., Chinappi, M. (2015) Multistep Current Signal in Protein Translocation through Graphene Nanopores. The Journal of Physical Chemistry B, 119, no. 18 (2015): 5815-5823.